The atmospheric deposition of nitrogen and sulfur and their relation to critical loads of atmospheric deposition is an important consideration for the preservation of national parks, wilderness areas, national monuments, wildlife refuges and other areas of interest.  In this paper, we investigate the deposition of nitrogen and sulfur compounds in Kansas, Oklahoma, and Texas using the advanced photochemical grid model, CAMx. The model simulates the atmospheric chemistry, dispersion and dry and deposition of nitrogen and sulfur emissions from diverse anthropogenic sources as well as natural sources such as wildfires and biogenic emissions. Estimated future deposition rates due to projected cumulative emission sources in 2030 are compared with critical loads of acidity for surface waters and forests, and to empirical critical loads for nutrient nitrogen. The analysis uses critical load values from the National Critical Load Database that are dependent on a specific site and ecoregion. Specifically, the comparison was performed for sulfur and nitrogen acidity at over 145 surface waters and over 100,000 modeled forest ecosystem locations and for empirical critical loads of nutrient nitrogen at several federal Class I areas to estimate future potential exceedances of critical loads for atmospheric deposition at these sensitive ecosystems.