Atmospheric NH₃is an important precursor to particulate matter, and it has effects on ecosystem stability, soil acidification, aerosol acidity, and climate change. Previous estimates of NH₃emissions in the US are quite uncertain both in terms of magnitude and seasonal variability. The most recent remote sensing measurements of NH₃from CrIS can provide constraints on NH₃sources at fine resolution, and with great spatial coverage and small noises. We conducted 4D-Var inversion experiments using high-resolution CrIS observations of NH₃profiles, GEOS-Chem, and its adjoint model to estimate NH₃emissions in the contiguous US for each month in 2014. Increases are found in CrIS-derived anthropogenic NH₃emissions across most of contiguous US on an annual scale, while slight decreases are found over Northern Iowa and Southern California from March to July. CrIS-derived anthropogenic NH₃emission estimates for the contiguous US is 4.27 Tg N a^-1, ~45% higher than the HTAP v2 emission inventory (2.95 Tg N a^-1). We evaluate our CrIS-derived NH₃emissions using monthly mean AMoN surface NH₃measurements in 2014. CrIS-derived monthly NH₃emissions increased the correlation coefficient between national monthly average of GEOS-Chem surface NH₃and AMoN surface NH₃ measuremnents from 0.33 to 0.82, and decreased the normalized mean bias (NMB) from -0.34 to 0.10 on an annual and national scale. We will further evaluate our CrIS-derived NH₃ emissions using NADP measurements of wet deposition of NH₄⁺in 2014.